Gmail is the best invention since slice bread. Well, maybe not, but it is definitely the best email client out there. Even hardcore Outlook users get hooked once they decide to give a try. There are several advantages: you can access it from anywhere and from any computer; you can integrate it with other Google tools and web apps; you can customize it extensively; and so on.
One advantage of using Gmail is that you can connect and use several email addresses from within your main account. For example, you could connect and use your Yahoo! account that you use for friends and relatives, your work email address and the email accounts of your own domain all under your Gmail account. This means that you would be able to receive AND send emails from all these accounts without leaving Gmail. Neat huh? To activate this you need to first forward the emails of your other email accounts to your Gmail address.