If you need social interaction through out the day, then working from home might not be ideal to you. There are people that just need to have others around at any given time; that need face to face communication, and for those a corporation might be a better fit.

Instant messaging clients, Twitter and social networks might help people to overcome this problem, but we all know that they are far from the real deal.

If you live alone this should not be a problem. If you live with your parents, friends or wife and kids, however, be prepared to get interrupted more often than not. Other people have a hard time to conceptualize that you are actually working when you are at home on your computer. As a result, they will knock on your door or call you even for the smallest of the issues.